Cervical Spinal Fusion: rhBMP Associated With Complications


The Journal of Bone and Joint Surgery recently included a report on complications in patients who underwent cervical spine surgery with recombinant human bone morphogenetic protein.

The study included 1 million patients from the Nationwide Inpatient Sample database who underwent cervical spinal fusion from 2003 to 2010. There were 7.96 percent who received rhBMP. The researchers found rhBMP was a significant predictor of complications:


•    Dysphagia
•    Dysphonia
•    Hematoma/seroma formation
•    Neurological complications


The complications were most common after anterior cervical fusion surgery, and wound infections and neurological complications were most common after posterior cervical fusion. Dysphagia was most common after circumferential fusion.


More Articles on Spine Surgery:
How Spine Outcomes Registries Are Transforming Treatment Form Dr. Neel Anand
36 Spine Surgeons Performing Artificial Disc Replacement
The Robotic Difference: How New Technology Could Impact Spine

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