9 acquisitions totaling $6B in the orthopedic device industry

Spinal Tech

Acquisitions are abundant within the spine and orthopedic device industry. Here are nine that were completed or announced in the last year that total more than $6 billion:

1. Bioventus is preparing to acquire Misonix, a spine-facing medtech company, in a $518 million deal. The transaction is expected to close in the fourth quarter and add almost $80 million to Bioventus' revenue in 2021.

2. Bioventus has made a $50 million escrow payment as part of its option and equity purchase agreement with Israeli medtech company CartiHeal, signaling its intent to proceed with a reported $500 million acquisition.

3. Alphatec acquired EOS imaging for a reported $116.9 million in May. The company is integrating EOS technology into its Alpha Informatix platform, adding spinal imaging and anatomical modeling.

4. SeaSpine bought 7D Surgical for a reported $110 million in May. The company's flagship technology is a radiation-free tool designed to assist surgeons placing spinal implants.

5. In February, NuVasive paid $150 million to acquire Simplify Medical, which developed an artificial disc that is being evaluated for two-level indications. 

6. Smith+Nephew acquired Integra LifeSciences' extremity orthopedics business for $240 million in January. The deal includes a shoulder replacement system the company expects to launch in 2022.

7. Integra LifeSciences acquired regenerative medicine company ACell in January. Terms of the deal include $300 million in cash at closing and up to $100 million more in cash payments if certain revenue growth milestones are met. 

8. In December, Zimmer Biomet acquired cardiothoracic surgery company A&E Medical Corp for $250 million. Revenue from the portfolio will be recognized in Zimmer Biomet's dental, spine and craniomaxillofacial and thoracic business unit before the company spins off into two separate entities, with NewCo expected to take on the spine and dental units in mid-2022.

9. Stryker completed its $4 billion acquisition of competitor Wright Medical Group in December. Stryker said Wright Medical, which develops extremity and biologic products, has preoperative planning technology and sufficient scale to enable the combined business to have a more focused business unit approach.

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