Posterolateral Lumbar Spinal Fusion: Does BMP Have Advantages?

Spine

A team of researchers recently published an article in Spine examining posterolateral instrumented lumbar fusion using rhBMP-2.

The multicenter prospective randomized controlled trial included 197 patients who received one- or two-level instrumented posterolateral lumbar fusion at one of eight participating institutions. The researchers followed patients for two to four years postoperatively and found:

 

•    No significant adverse events attributed to the study drug when compared with controls.
•    The control group experienced significantly more graft-site complications than one may expect.
•    The two groups had similar 36-Item Short Form Health Survey, Oswestry Disability Index and leg/back pain scores.
•    Around 94 percent of the patients who received rhBMP-2 reported radiographical fusion rates, compared with 69 percent of the patients who received autograft.

 

As a result of their findings, the researchers suggest that "use of rhBMP-2 should be considered in cases where lumbar arthrodesis is of primary concern."

 

More Articles on Spine Surgery:
19 Spine Devices Receive FDA 510(k) Clearance in November
A New Generation of Spine Surgeons: How Minimally Invasive Techniques Impact Training
Cervical Spinal Fusion for Trauma: 5 Outcomes & Cost Differences for Weekend Admits

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