20 major orthopedic device company acquisitions in 2019 so far

Spinal Tech

The medical device mergers and acquisitions market has been active this past year.

Here are 20 major transactions in the orthopedic and spine field.

DePuy Synthes will acquire the assets of JointPoint in a deal that is set for completion by the end of the year. The company will acquire JointPoint's navigation software, which it plans to develop for further orthopedic procedures. Neither company disclosed financial details of the deal.

Linden Capital Partners acquired Collagen Matrix. The company's collagen products can be used in a variety of applications including the device sectors of neurosurgery, orthopedics, spine and sports medicine. Financial terms of the deal were not disclosed.

Stryker signed a definitive agreement to acquire point-of-care imaging technology company Mobius Imaging and its sister company Cardan Robotics for $370 million in an all-cash transaction and stands to pay up to $130 million more if the company meets certain milestones. Stryker expects to close the acquisition in the fourth quarter.

Earlier this year, Stryker also acquired OrthoSpace, an Israel-based company focused on technology to treat irreparable rotator cuff tears, for $10 million cash upfront and $110 million if the company meets future milestones.

Boston Scientific acquired Vertiflex, the developer of Superion Indirect Decompression System, for $465 million in upfront cash. The company could make additional payments if Vertiflex reaches certain milestones in the next three years.

OrthoPediatrics acquired Vilex, a foot and ankle surgical device company, for $50 million cash and $10 million in stock. Vilex has both an adult and a pediatric portfolio.

Smith & Nephew closed its acquisition of Brainlab, boosting its orthopedic joint replacement business. Smith & Nephew will begin integrating the Brainlab platform into the next version of its robotic surgery platform, Navio 7.0.

Exactech expanded its reach in the foot and ankle market with the acquisition of medical device company EPIC Extremity, which designs bone and joint restoration products and biologic solutions for extremities, knees and hips.

Global pediatric orthopedic company WishBone Medical acquired CSpine. This is Wishbone's third acquisition in the past six months; it acquired Response Ortho and Red Star Contract Manufacturing in November last year.

Denver-based intraoperative neuromonitoring company Assure Holdings acquired Parker, Colo.-based professional IONM company, Littleton Professional Reading, for $700,000. Little managed around 375 spine and neurosurgery cases in 2018.

New York-based medical device manufacturer Misonix agreed to acquire privately held wound-healing company Solys Medical of Newport News, Va., in an all-stock transaction valued at $97 million. The boards of both companies approved the deal, which is slated for completion in the third quarter of 2019.

Smith & Nephew acquired Osiris Therapeutics, a bone graft and articular cartilage substitute products company, for $660 million.

RTI Surgical completed the up to $300 million acquisition of Paradigm Spine.

Pacira acquired Myoscience, a medical device company focused on targeted therapies for pain relief, for $120 million in cash upfront and another potential $100 million pending commercial and regulatory milestones.

Smith & Nephew acquired Brainlab's orthopedic joint reconstruction business.

Brainlab acquired application-specific robotic technologies developer Medineering, marketing under the name Cirq, which will expand its reach into the ASC industry.

European private equity firm Nordic Capital acquired majority holding in Orchid Orthopedic Solutions from Altor Fund III for an undisclosed sum.

SpineSource acquired intellectual property assets of two spinal implant systems from Kisco International, a French company, including the L-Varlock Expandable Lumbar Cage.

Orthofix acquired Options Medical, a medical device distributor based in Florida, for an undisclosed amount.

Kyocera purchased major assets of Renovis Surgical technologies related to artificial joint and spine products.

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