14 acquisitions in the orthopedic device industry in 2022


After a brief lull in mergers and acquisitions among orthopedic device companies because of the COVID-19 pandemic, market activity is picking back up again.

Here are 14 acquisitions in the orthopedic industry this year:

1. Onkos Surgical, which specializes in musculoskeletal oncology and complex orthopedics, entered into a definitive agreement to acquire Stryker's Juvenile tumor system.

2. Enovis acquired Insight Medical Systems, developer of an augmented-reality system for knee and hip replacement.

3. Enovis also acquired 360 Med Care, an Australian startup focusing on total joint replacement technologies.

4. OrthoPediatrics spent $33 million to acquire Pega Medical, a device company that has developed six implants and one instrument for the treatment of musculoskeletal disorders and diseases.

5. OrthoPediatrics also acquired MD Orthopaedics for $19.6 million. The company develops a custom bracing system for club foot.

6. Private equity-backed TheraCell acquired Isto Biologics, which specializes in bone regeneration and cell-based therapies for orthopedics.

7. Medartis purchased Nextremity Solutions for up to $70 million with milestone earnout payments of up to $30 million. The deal will help Medartis accelerate its U.S. extremities business.

8. Conmed spent $145 million to acquire In2Bones, a devicemaker focused on upper and lower extremities. 

9. ORHub, a healthcare analytics company, broke into the medtech market after acquiring Pur Biologics. 

10. Bioventus has exercised its call option to acquire Israeli devicemaker CartiHeal for up to $450 million following the FDA's premarket approval of the Agili-C implant. The transaction is expected to close in the third quarter.

11. Surgalign Holdings acquired an equity interest in Interneural Networks, which developed an artificial intelligence technology that identifies possible pathological states.

12. Paragon 28, a foot and ankle devicemaker, acquired preoperative planning software company Disior for $18 million at closing and up to $8 million if certain milestones are reached.

13. Smith+Nephew acquired Engage Surgical, which has the only cementless partial knee system commercially available in the U.S. The deal will cost up to $135 million, depending on sales performance.

14. Stryker acquired Vocera Communications for $3.1 billion in a deal that aims to enhance the company's digital healthcare business.

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