Study: BioSeed-C Shows Good Graft Implantation, Reduction in Strength

A long term study of BioSeed-C treatment for degenerative cartilage defects of the knee shows that graft implantations are good after four years, but there is a persisting strength deficit, according to a study published in The American Journal of Sports Medicine.

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Researchers conducted a four-year follow-up on 52 patients with full-thickness cartilage defects who were treated with BioSeed-C. Nearly all patients showed significant improvement in the Lysholm score, International Knee Documentation Committee score, International Cartilage Repair Society score and Knee Injury Osteoarthritis Outcome Score

In the MRI evaluations, researchers found a moderate to complete defect filling in 43 of the 44 treated patients. There were two patients without clinical and MRI improvements and they received a total knee endoprosthesis after four years. The Isokinetic evaluation reported a significantly reduced maximum strength capacity for knee flexion and extension.

Read the abstract about BioSeed-C.

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