8 spine, orthopedic studies to know

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From findings on cervical disc replacement to total knee replacement, Becker’s reported on eight spine and orthopedic studies since March 14.

1. Cervical disc replacement is a safe option across all obesity levels compared to anterior cervical discectomy and fusion, according to a study in the April 2025 issue of The Spine Journal.

2. A study reviewing same-day discharge patient outcomes undergoing total knee arthroplasty in the ASC versus the tertiary-care university hospital setting determined that, while ASCs have stricter requirements for TKA patients, they have similar outcomes to same-day hospitals. 

3. Having a higher socioeconomic status is associated with greater rates of surgical resource usage before spinal fusions, according to a study in the April 2025 issue of The Spine Journal.

4. Patients with metal joint replacements may have significantly higher concentrations of cobalt, chromium, titanium, niobium and zirconium in their blood and cerebrospinal fluid, according to a March 28 study published in JAMA Network Open.

5. Researchers at UMass Chan Medical School in Worcester, Mass., have created an algorithm to predict total knee replacement outcomes in patients five years post-surgery. Researchers identified five predictors of patient outcomes, including patient age, BMI, medical and musculoskeletal comorbidities, baseline pain and functional status, and mental health.

6. A study found that Aurora Spine’s SiLO TFX sacroiliac fusion system saw stronger outcomes compared to traditional posterolateral transosseous techniques.​ The clinical study, published in Neurospine, found SiLO TFX removed less bone volume and offered a larger surface area for bony fusion compared to the posterolateral transosseous technique and maintained the bone-implant interface upon fatigue loading in all specimens.

7. Patients having two-level cervical disc replacement tended to have fewer postoperative complications compared to those having two-level anterior cervical discectomy and fusion, according to a study published in the April 15 edition of Spine.8. Taking prescription sleep medications within 90 days of knee replacement surgery may be linked to dislocations of the prostheses, revision surgery, falls, wrist fractures and visits to the emergency department, according to a study presented at the 2025 annual meeting of the American Academy of Orthopaedic Surgeons.

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