Researchers tested 124 patients who received 1.5 or 3 grams of tranexamic acid in 100 mL of normal saline solution or an equivalent volume of placebo applied to the joint for five minutes at the end of surgery.
Of the 99 patients who completed the study, postoperative blood loss was decreased among the tranexamic acid groups compared with the placebo group. There was no difference in deep-vein thrombosis or pulmonary embolism between the groups.
Read the abstract for “Topical Application of Tranexamic Acid Reduces Postoperative Blood Loss in Total Knee Arthroplasty.”
Read other coverage on knee surgery:
– Study: Double-Bundle PCL Reconstruction Using a Single Sling an Effective Procedure
– New in Knee Surgery: Personalized Knee Resurfacing Implants
