Rheumatoid arthritis: Link between depression and poorer health outcomes — 5 takeaways

Researchers utilized the European Quality of Life 5 Dimensions scale to measure depression/anxiety in rheumatoid arthritis patients and followed 379 patients for two years. Their findings indicated patient with rheumatoid arthritis who exhibited symptoms of depression and/or anxiety were more likely to have poorer health outcomes and decreased treatment response, according to Medscape.

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Here are five takeaways from the study.

 

1. Researchers identified consistent relationships between depression/anxiety and subjectively measured components of the 28-Joint Disease Activity Score.

 

2. Patients who presented symptoms of depression/anxiety had decreased odds of attaining rheumatoid arthritis remission at two years.

 

3. Researchers found baseline depression/anxiety was linked with a 50 percent reduced prednisone treatment response in this patient population.

 

4. Lead researcher, Faith Matcham, stated the findings do not indicate there is a casual relationship between mental health and RA outcomes, but a bidirectional relationship. She writes, “Our results suggest that symptoms of depression/anxiety may reduce the body’s ability to respond to glucocorticoid treatment.”

 

5. The data suggests patients may have a better treatment response if they are provided with enhanced management of mental disorders. Researchers call for more studies to determine if this hypothesis is correct.

 

More articles on orthopedics:
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