Researchers received the Kappa Delta Award from the American Academy of Orthopaedic Surgeons and the Orthopaedic Research Society for their work with mice, which could be promising for post-traumatic osteoarthritis, which annually affects 6 million people in the United States.
“The traditional approach is to take a complicated problem like a knee fracture, and dissect it and look at each element — the load that goes across the joint, the force that’s transmitted to the bone and cartilage, the blood and inflammation,” Steven Olson, MD, of Duke University and principal investigator told The Herald Sun. “While these pieces are interesting, all of these things are happening at once. It’s hard to make sense of these pieces in isolation. We needed to look at the joint as a whole. The big step was creating the model.”
According to the report, the model was a closed-joint experimental model of a knee fracture so researchers could study post-traumatic inflammation and the onset of osteoarthritis in mice.
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