Biologics

One of the most common criticisms I hear about peptides in orthopedics is straightforward: there isn’t enough human data. I agree. For compounds commonly discussed in orthopedics such as BPC-157, the preclinical literature is interesting, but the human musculoskeletal evidence…

Vector Science and Therapeutics, a medical technology and therapeutic delivery company, filed a provisional patent application covering a platform designed to improve tissue healing in orthopedic surgical care. The platform pairs tissue-repair-promoting peptides with a patient’s own platelet-rich plasma or…

Stefano Sinicropi, MD, an orthopedic spine surgeon, was appointed to Genesis Regenerative’s clinical advisory board. Dr. Sinicropi is president and CEO of Edina, Minn.-based Midwest Spine & Brain Institute and founder of HyperCharge Health, an integrative clinic offering nonsurgical care,…

GelrinC, Regentis Biomaterials’ cartilage-repair technology, received a Japanese Notice of Allowance for patent protection covering its organic solvent-free manufacturing process and ready-to-use liquid formulation. The Japanese patent allowance followed a recent U.S. patent issuance and expanded the company’s global intellectual…

Regenerative medtech company Isto Biologics has acquired regenerative medicine developer NovaBone Products, adding a portfolio of synthetic bioactive glass bone grafts to its orthobiologics business. NovaBone develops synthetic bone graft products based on proprietary bioactive glass technology that are sold…

Pensacola, Fla.-based Regenative Labs published an observational study in Medical Research Archives documenting reduced pain and increased quality of life in patient-reported outcomes for 31 individuals who received cryopreserved human umbilical cord tissue allograft applications for defects affecting the paraspinal…

A few years ago, Omar Rahman, MD, rarely heard the word “peptide” in an orthopedic exam room. Now patients arrive asking about BPC-157, TB-500 and growth-hormone-related compounds after hearing about them from friends, podcasts, Reddit threads or social media. They…

Regentis Biomaterials is targeting an estimated $3 billion U.S. cartilage repair market with GelrinC, an investigational hydrogel-based implant designed to regenerate damaged knee cartilage through a single-step procedure. GelrinC is designed as an off-the-shelf cartilage repair platform that can be…

An observational study published in Biomedicines evaluated 117 patients who received one to three applications of cryopreserved human umbilical cord tissue allografts for thoracic and lumbar paraspinal muscle and entheses defects. The study, which included patients across 11 clinics with…

Houston-based TYBR Health, a medtech and orthopedic regenerative medicine company, has secured $30 million in a Series A financing round.  The company will use the funds to expand commercial access to its FDA-approved B3 GEL System, broaden its product indications…