Orthopedic surgeons performed the procedure on 30 patients with knee chondral or osteochondral lesions. The multilayer gradient nano-composite scaffold was obtained through nucleating collagen type 1 fibrils with hydroxyapatite nanoparticles and the scaffold was implanted into the patients’ knees.
The Tegner and International Knee Documentation Committee scores improved significantly from baseline at all evaluations to the 24-month follow-up. There were similar results for patients who experienced adverse events and a slower recovery process. Active patients recovered the quickest.
The complete filling of the cartilage and integration of the graft was shown in 70 percent of the lesions.
Read the abstract about the new cartilage regeneration technique.
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