The researchers applied human chondrocytes to Chondro-Gide collagen membranes at a 12 million cell volume. During the first experiment, two sterile marker pens (one containing methylene blue and the other crystal violet inks) marked the membranes immediately before adding cells. For the second experiment, the same marker pens marked membranes seven days after the cell culture.
Control membranes without any ink showed cell viability approaching 100 percent. Cell viability among those marked with methylene blue (23.1 percent) and crystal violet (18.9 percent) were significantly lower adjacent to the ink mark on the smooth side for group B and on the porous side from the ink in group C.
Read the abstract on the report about marked cell viability.
Read other coverage on sports medicine studies:
– 8 New Studies Influencing Sports Medicine
– Study: Matrix-Induced Autologous Chondrocyte Implantation Suitable for Treating Knee Cartilage Defects
– Quality Metrics and Sports Medicine: 4 Key Considerations
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