Periprosthetic Joint Infection Identifiable With Leukocyte Esterase Reagent Strips

In an award-winning presentation at the annual meeting for the American Association of Hip and Knee Surgeons, surgeons and researchers found that using leukocyte esterase reagent strips can be helpful in diagnosing periprosthetic joint injection quickly, according to an AAOS Now report.

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The study included 223 patients who were suspected of having PJI after total joint arthroplasty. There were 180 patients who underwent knee procedures and 43 patients who underwent hip procedures. Sixty-seven patients underwent testing in the OR while 156 patients underwent testing in the office.

After applying the LER strip, 52 patients were positive and 106 were negative. Results were not identifiable in the 65 remaining strips. The LER strips had 92.2 percent sensitivity and 88.8 percent specificity. The strips had 100 percent sensitivity and 86.8 percent specificity in the 67 re-operations, according to the report.

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