He reviewed studies, including his own, which conducted rotator cuff surgeries with the use of a platelet-rich plasma fibrin matrix, and the clinical outcomes were not significantly improved.
Dr. Weber said little evidence supports the favorable reputation of PRP among injured athletes. He questions the safety of the products, too, because of reports of carcinogenesis associated with bone morphogenetic protein. Also, since PRP is considered an investigational product, insurance companies will not reimburse for its use.
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