Study: Lumbar Disc Disease May Have Hereditary Disposition

The excess relatedness of patients with lumbar disc disease and the elevated risks to near and distant relatives suggests that symptomatic lumbar disc disease could be hereditary, according to an article published in The Journal of Bone and Joint Surgery.

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The Utah Population Database was examined to identify patients with a diagnosis of either lumbar disc herniation or lumbar disc degeneration. Genealogic data was also recorded.

The Genealogical Index of Familiarity, comparing the average relatedness of affected individuals, tested for 1,264 patients with lumbar disc disease showed a relatedness of p<0.001. The relative risk in relatives was significantly elevated in both first-degree and third-degree relatives.

Read the abstract for “Evidence for an Inherited Predisposition to Lumbar Disc Disease.”

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