5 points on adjacent segment degeneration, disease after cervical disc arthroplasty

Laura Dyrda -   Print  |

A study published in The Spine Journal examines adjacent segment disease in patients who undergo cervical disc arthroplasty.

The researchers examined data from MEDLINE, SCOPUS and Web of Science studies for articles reporting adjacent segment degeneration or adjacent segment disease after cervical arthroplasty. There were 1,891 articles reviewed and 32 that met inclusion criteria.


The researchers found:


1. Among cervical arthroplasty patients, 8.3 percent reported adjacent segment degeneration and 0.9 percent reported adjacent segment disease. The adjacent segment degeneration at individual levels was 10.5 percent and adjacent segment disease at individual levels was 0.2 percent.


2. The studies found 5.1 percent of the patients followed for one to two years reported adjacent segment degeneration and 0.2 percent reported adjacent segment disease.


3. When patients were followed for more than 24 months, the incidence adjacent segment disease and degeneration rates were higher; adjacent segment degeneration was reported in 16.6 percent of the patients and 2.6 percent reported adjacent segment disease.


4. Among patients who underwent one-level procedures, 7.4 percent reported adjacent segment degeneration while 15.6 percent of patients who underwent two-level procedures reported the same. There was an 8.2 percent increase in adjacent segment degeneration after the two-level procedures, but this wasn't statistically significant.


5. The one-level cervical arthroplasty procedures showed 0.8 percent of the patients had adjacent segment disease. The study authors were unable to analyze data about adjacent segment disease among two-level cervical arthroplasty patients.


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5 key notes on the European spine devices market

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