Spinal Fusion Pain & Long-Term Outcomes: Better With Pregabalin?

Written by Laura Dyrda | March 25, 2014 | Print  |

In a prospective, double-blind, randomized control trial, researchers examined the postoperative pain and long term functional outcomes for spine surgery patients who received gabapentin and pregabalin and published the results in Spine.

The study included 90 patients with one group receiving 300 mg of gabapentin, a second group receiving 75 mg of pregabalin and a third group receiving a placebo dose one hour before surgery and eight hourly for seven days thereafter.


The patients who received pregabalin consistently showed reduced static and dynamic pain and required less rescue drug during the postoperative period. "Preoperative pregabalin administration is associated with less pain intensity and improved functional outcomes three months after lumbar discectomy followed by gabapentin and then placebo," concluded the study authors.


More Articles on Spine Surgery:
Minimally Invasive vs. Open Spine Surgery: Where the Field is headed
Spine Surgery vs. Nonoperative Treatment for Cervical Spine Facet Fractures
30 Spine Surgeons With Interest in Sports Medicine

© Copyright ASC COMMUNICATIONS 2019. Interested in LINKING to or REPRINTING this content? View our policies here.

Top 40 Articles from the Past 6 Months