Study Shows Good Results for IV Acetaminophen Administration for Pediatric Spine Surgery


Intravenous administration of acetaminophen for adolescents undergoing major spine surgery can safely relieve pain, according to a study presented at the Scoliosis Research Society annual meeting, according to an AAOS Now report. In a randomized, placebo-controlled, double-blind study conducted at the Helsinki and Turku Children's Hospitals in Finland, researchers examined 36 patients who either received IV acetaminophen for 15 minutes or a placebo of intravenous saline. Additional doses of acetaminophen or the placebo were administered at eight and 16 hours after the initial dose.

No differences were found in the Objective Pain Scale between the two groups after removing the tracheal tube. The time from ending anesthesia to removing the tracheal tube was shorter for the patients who received acetaminophen and the first patient-controlled administration of oxycodone was 28 minutes shorter for the placebo group.

Of the patients who reported visual analog scale scores of six or more, the patients in the acetaminophen group experienced that level of pain for a shorter amount of time. There were not differences in oxycodone consumption between the two groups during the first 24 hours.

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