The researchers examined data from prospective FDA regulated Mobi-C artificial disc replacement study; the control group included 81 one-level ACDF patients and 105 two-level ACDF patients. The researchers found:
1. Many of the pain scores improved significantly in both groups. The measures that improved include:
• Neck Disability Index scores
• Visual analog scales assessing neck and arm pain
• SF-12 scores
2. There was a significant difference at 60 months for the two groups for the NDI and SF-12 PCS scores.
3. In the one-level group, there was a 93.3 percent fusion rate after 60 months; the two-level group reported 86.1 percent fusion rate. The difference wasn’t significant.
4. There was adjacent segment degeneration found in 54.7 percent of the patients at the superior level for the one-level patients. Adjacent segment disease at the inferior level occurred in 44.7 percent of the patients in the one-level group.
5. In the two-level group, 70.8 percent of the patients reported adjacent segment degeneration at the superior level and 55 percent reported degeneration at the inferior level.
6. There was subsequent index level surgery performed in 11.1 percent of single-level patients compared with 16.2 percent of the two-level group. The difference wasn’t significant.
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