Here are the big acquisitions in the orthopedic and spine device space announced so far in 2019.
1. Medtronic finalized a $1.7 billion acquisition of Mazor Robotics after making a series of investments over the past two years.
2. Smith & Nephew acquired Osiris Therapeutics, a bone graft and articular cartilage substitute products company, for $660 million.
3. RTI Surgical completed the up to $300 million acquisition of Paradigm Spine.
4. Stryker acquired OrthoSpace, an Israel-based company focused on technology to treat irreparable rotator cuff tears, for $10 million cash upfront and $110 million if the company meets future milestones.
5. Pacira acquired Myoscience, a medical device company focused on targeted therapies for pain relief, for $120 million in cash upfront and another potential $100 million pending commercial and regulatory milestones.
6. Smith & Nephew acquired Brainlab's orthopedic joint reconstruction business.
7. Brainlab acquired application-specific robotic technologies developer Medineering, marketing under the name Cirq, which will expand its reach into the ASC industry.
8. European private equity firm Nordic Capital acquired majority holding in Orchid Orthopedic Solutions from Altor Fund III for an undisclosed sum.
9. SpineSource acquired intellectual property assets of two spinal implant systems from Kisco International, a French company, including the L-Varlock Expandable Lumbar Cage.
10. Orthofix acquired Options Medical, a medical device distributor based in Florida, for an undisclosed amount.
11. Kyocera purchased major assets of Renovis Surgical technologies related to artificial joint and spine products.