Orthopedic care is a high-demand target for private equity groups, PE Hub reported April 24, with the outpatient shift driving a significant portion of recent investment and growth.
While there have been several large PE-backed orthopedic platforms created or acquired in the last several years, the sector is still “highly fragmented and ripe for roll-up strategies,” according to the report.
Here are five recent deals driving PE’s uptick in orthopedics activity in the last six months:
1. PE firm Cinven announced its intent to invest in Regenity Biosciences in February. The contract development and manufacturing organization, which specializes in bioresorbable technologies, already received backing from Paramus, N.J.-based Linden Capital Partners when it was called Collagen Matrix. The deal is expected to close in the second quarter of 2026.
2. Gemspring-backed Zaviation acquires Choice Spine. ChoiceSpine was founded in 2006 and develops spine implants and instruments. Flowood, Mississippi-based Zavation’s acquisition expanded the company’s product portfolio and leveraged a vertically integrated manufacturing platform to accelerate innovation. Zavation, a spinal implant manufacturer, was acquired by Westport-, Conn.-based PE group Gemspring in 2021.
3. Healthcare Holding Schweiz buys PlusORTHO Prothetik. HHS, backed by KKA Partners and Winterberg Advisory, acquired Swiss orthopedic implant producer PlusORTHO in January, according to the report.
4. Poly Medicure acquires Archimed-backed Citieffe. In November 2025, Archimed announced the closing sale of orthopedic implants producer Citieffe to Poly Micure. The Italian device maker’s annual sales have increased by double-digit percentages in the trauma and orthopedic extremities market, according to the report.
5. InTandem-backed Sequel Ortho acquires Fox Valley Orthopedics. Geneva, Ill.-base Fox Valley Orthopedics joined Sequel Ortho, a management services organization in November. Sequel Ortho spans across Nebraska, Iowa and Illinois. Physician Growth Partners was the exclusive advisor to the partnership with Fox Valley Orthopedics.
At the Becker’s 32nd Annual Meeting: The Business and Operations of ASCs, taking place October 29-31 in Chicago, ASC leaders, surgeons and healthcare executives will explore strategies to drive growth, enhance operational performance, navigate reimbursement challenges and prepare for the future of ambulatory surgery. Apply for complimentary registration now.