San Diego-based Scripps Health received a $12.7 million orthopedic research grant from the California Institute for Regenerative Medicine, according to an April 13 news release shared with Becker’s.
The grant will go towards preclinical studies and planning for stem cell research involving knee injuries, led by investigators at the Shiley Center for Orthopaedic Research and Education at Scripps Clinic. It will support laboratory-based tissue engineering and cartilage and bone injury repair surgeries in animal models.
Researchers plan to demonstrate the safety and efficacy of engineered, scaffold-free tissue for knee injuries.
At the end of the five-year grant period, researchers plan to submit an investigational new drug or biological product application with the FDA.
“A biological implant that can successfully treat cartilage and bone defects of the knee would resolve the limited availability of donor graft tissue and has the potential to delay and eventually eliminate the need for joint replacement,” Darryl D’Lima, MD, PhD, orthopedic director and the study’s investigator, said in the release.
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