Aspirin effective in preventing venous thromboembolism after TKA, study shows — 3 insights

Orthopedic

Aspirin is as effective as rivaroxaban in preventing venous thromboembolism after total hip or knee arthroplasty, a study in The New England Journal of Medicine found.

Here are three things to know:

 

1. The study authors performed a multicenter, double-blind, randomized controlled trial involving 3,424 patients. Patients underwent total hip or total knee arthroplasty.

 

2. All patients received 10 milligrams of oral rivaroxaban for five days postoperatively and then were randomly assigned to continue rivaroxaban or switch to aspirin.

 

3. Venous thromboembolism occurred in 0.64 percent of patients in the aspirin group and 0.70 percent of patients in the rivaroxaban group. Extended prophylaxis with aspirin was not significantly different from rivaroxaban in the prevention of symptomatic venous thromboembolism in patients who underwent total hip or knee arthroplasty.

 

More articles on orthopedics:

Orthopedic surgeon to know: Dr. John Barker of the Rocky Mountain Spine Clinic

Younger total shoulder arthroplasty patients likely to return to work 2.1 months after surgery: 5 things to know

Orthopedic surgeon to know: Dr. Robert Arciero of UConn Health

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