Researchers gathered data from an electronic database and references from eligible articles. Comparative studies reporting on the results of primary spinal fusion including treatment group of NSAIDs perioperatively were regarded eligible.
Five retrospective comparative studies were included where none of the patients received NSAIDs for longer than 14 days following surgery. High-dose ketorolac showed a statistically significant adverse effect on spinal fusion with no statistical heterogeneity. Normal-dose NSAIDs did not produce inferior results when compared with the no-NSAIDs group.
Read the abstract about anti-inflammatory use for spinal fusions.
Read other coverage on spine surgery studies:
– Study: Asymmetric Pelvic Bones in Pediatric Cerebral Palsy Patients Affects Spine Surgery Technique
– Study: Rigid Occipitocervical Construct Best During Cervical Spine Surgery
– 5 Points on Cervical Spine Surgery
