Researchers infused the antioxidant into plastic that is commonly used to coat metal joint replacement implants and tested the antioxidant in a mouse model.
Here are four insights:
1. The COVERNOX-infused particles resulted in a net gain of new bone, whereas the non-infused particles showed no net gain or loss.
2. The researchers tested COVERNOX on smooth bone rather than an articulated joint.
3. However, Edward Schwarz, PhD, director and Richard and Margaret Burton Distinguished Professor of Orthopaedics in the Center for Musculoskeletal Research at URMC, said the results are applicable to human joints.
4. DePuy Synthes plans to conduct more clinical trials for COVERNOX. The trials have yet to receive FDA approval.
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