The prospective randomized study analyzed 1,483 patients that received the antibiotic-infused cement during knee arthroplasty and 1,465 patients that received cement not loaded with antibiotics. The rate of both superficial and deep infection was similar in both groups.
The study concluded that cement loaded with antibiotics is not suggested for use in the general population, but should undergo further study to determine its efficacy in patients at a high risk for infection.
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