A new study published in Spine examines the minimum clinically important difference threshold for Scoliosis Research Society-22R patients.
The researchers examined data from adult spinal deformity patients who underwent surgical correction and completed the SRS-22R postoperatively and then the SRS-20 at one year after surgery. There were 1,321 patients included in the study who were 53 years old on average.
The average body mass index was 26.3. Here are six findings from the study:
1. The average postoperative SRS-22R appearance score was 2.50. The score improved to 3.62 on average one year after surgery.
2. The average SRS-22R activity score was 2.96 postoperatively and improved to 3.33 one year after surgery.
3. The average SRS-22R pain score was 2.73 postoperatively. One year after surgery, the average score was 3.60.
4. The average postoperative total score was 2.93, which improved to 3.65 one year after surgery.
5. The researchers noted a statistically significant difference in the domain scores among responses to the anchors, according to the study abstract.
6. The MCID values were:
• Appearance: 0.19 to 1.23
• Activity: 0.23 to 0.60
• Pain: 0.24 to 0.57
• Subscore: 0.16 to 0.43
• Total score: 0.17 to 0.71
"When combined with previous reports, the results of this study in a population with adult spinal deformity undergoing surgical treatment show MCID for SRS-22 scores can be estimated as 0.4," concluded the study authors. "This corresponds to a change of one interval in two of the five questions for a single domain."