Chicago-based Northwestern University researchers developed a synthetic bone with a 3D printer, according to wttw. The synthetic bone is able to stimulate new bone growth.
Science Translational Medicine will publish the research findings.
Here are nine highlights:
1. Ramille Shah, PhD, assistant professor in the materials science and engineering department and surgery transplant division at Northwestern, headed the development of the synthetic bone.
2. Dr. Shah and her team created a "unique 3D ink formulation" to create printed 3D objects composed of the mineral in natural bone tissue. The remaining part of the formula is biocompatible and biodegradable.
3. The researchers described the printed product as hyper-elastic bone. This high elasticity allows for an easily cut, rolled and folded bone material.
4. The elasticity also provides for a porous and absorbent material, which promotes cell and tissue integration.
5. Printed at room temperature, the hyper-elastic bone may be created in bulk or individualized.
6. Other Northwestern researchers then tested the efficacy of the hyper-elastic bone, investigating whether an adult stem cell would survive on the bone without additives. The study revealed the stem cells differentiated into osteoblasts.
7. The researchers then tested the bone in a mouse and found the cells accepted it.
8. An additional study found the hyper-elastic bone promoted bone growth in rodents' spines.
9. Dr. Shah said they strive to use hyper-elastic bones in humans within five years.